Resident Physicians[edit]

NameActor/actressStarring seasonsRecurring seasonsOccupation at Grey Sloan (or its predecessors)Job Title
Stephanie EdwardsJerrika Hinton10 , 11, 12, 139General Surgical ResidentM.D.
An intern on Season 9, Stephanie Edwards is similar to Cristina Yang, as she has high hopes for her surgical career. Despite this, she starts dating Jackson Avery after he breaks up with April Kepner, although they break up when Jackson stops April's wedding by professing his love for her. Stephanie then dates a patient, Kyle, but they break up in the days leading up to his death, leaving an emotional impact on her. She leaves at the end of Season 13 following a fire at the hospital to live life outside of a hospital, which she hasn't known since she spend her childhood in hospitals sick.

Alexandra "Lexie" GreyChyler Leigh4, 5, 6, 7, 83General Surgical ResidentM.D.
Resident and half-sister of Meredith Grey, Lexie Grey attended Harvard Medical School. She has had relationships with Mark Sloan, Alex Karev, and Jackson Avery. Known for her photographic memory, she has earned the nickname "Lexipedia." Initially she has a distant, contentious relationship with Meredith, but they eventually grow closer. She is often called "Little Grey" by other doctors on staff. In Season 8, she professes her love for Mark, but he does not tell her he loves her back until the plane crash. She dies from her injuries while holding onto Mark.

Leah MurphyTessa Ferrer109, 13General Surgical ResidentM.D.
An intern on Season 9, Leah Murphy briefly sleeps with Alex Karev, who is having sex with intern after intern at the time. She often asks her fellow interns questions related to Alex and seems to be hung up on him. She has an affair with Arizona Robbins while Arizona and Callie Torres ware separated. However, when Arizona ends their tryst to repair her marriage, Leah becomes hung up on her and hopes for their marriage to end, going as to report her and Arizona's relationship to the hospital. In Season 10, Leah is told by chief Webber that surgery is not for her, and that she should leave the program.

George O'MalleyT.R. Knight1, 2, 3, 4, 5N/AGeneral Surgical ResidentM.D.
George O'Malley has a less aggressive personality compared to his fellow residents. He has an infatuation with Meredith Grey, which ends when they sleep together and, halfway through, Meredith begins to cry and ultimately rejects him. He has a strong friendship with Izzie Stevens and, later, Lexie Grey. He was once married to Callie Torres, but their marriage came to an end when George slept with Izzie. George and Izzie attempt to have a relationship but decide to remain friends when they realize that their relationship lacks chemistry. Inspired by Owen Hunt's experiences, George decides to leave Seattle Grace and enlist in the Army. Tragically, on his way to tell his mother about joining the Army, George dies when he prevents a girl from being hit by a bus, sacrificing himself instead.

Shane RossGaius Charles109General Surgical ResidentM.D.
An intern on Season 9, Shane Ross aims to be "the new Shepherd" and even assists on Derek's hand surgery. However, he is frustrated when Derek chooses Heather Brooks as his intern because of her quick reflexes. In Season 10, after he sticks up for Cristina Yangwhen she and Meredith fight over the 3D printer, he and Yang start a sexual relationship, which only lasts briefly. Later in the season, Ross almost kills a patient, as sleep deprivation causes him to have a mental break down. In the Season 10 finale, Ross leaves Seattle for Zurich with Cristina, as he wants to learn from her.

Isobel "Izzie" StevensKatherine Heigl1, 2, 3, 4, 5, 6N/AGeneral Surgical ResidentM.D.
After growing up in a trailer park and putting her newborn daughter up for adoption at age 16, Izzie Stevens managed to advance through medical school by modeling to pay her bills. She puts her career as doctor on the line in a risky bid to get her fiancé, Denny Duquette, a new heart by cutting his LVAD wires. Denny subsequently dies, but Izzie manages to keep her job following invasive therapy sessions put up by the hospital. She then begins a relationship with Alex Karev, and they eventually get married. Their relationship becomes strained when she is diagnosed with metastatic melanoma. She recovers following treatment with Interleukin 2 but after, returning to work, she accidentally induces hyperkalemia in a patient listed for a renal transplant. Subsequently, she loses her job and leaves Seattle. She and Alex divorce, and she is never seen again.

Josephine "Jo" WilsonCamilla Luddington10, 11, 12, 13, 149General Surgical ResidentM.D.
An intern on Season 9, Jo Wilson is at first made fun of by Alex Karev, who believes she's a rich girl and nicknames her "princess." On the contrary, she had a cruel childhood and has had to work very hard in order to get through life and become a doctor. Alex gradually warms up to her, and they become close friends. She starts a relationship with an obstetrician, causing Alex to become jealous. She is set to move in with her boyfriend, but they get in a physical fight in which he becomes severely injured. After she leaves her boyfriend, Alex confesses his love to Jo. They start dating but have relationship issues in Season 11 when she turns down Alex's marriage proposal. Things only worsen when Alex beats up Andrew DeLuca after finding him and Jo in a compromising situation, landing Alex in jail for a brief period. Jo has trust issues with Alex, as she believes he could physically hurt her, but she forgives him once she discovers that Alex had tracked down her ex-husband, Paul, but didn't beat him up. In Season 14, Paul comes to Grey Sloan to sign divorce papers from Jo, whom he calls "Brooke", since she changed her name and ran away when they separated. Paul is still the same manipulative and abusive husband that he was years ago, and that scares Jo into signing the papers. Paul threatens Jo's life, but he is soon after killed during a hit-and-run, freeing Jo of her past. Later, she and Alex finally get engaged.

Intern physicians[edit]

NameActor/actressStarring seasonsRecurring seasonsOccupation at Grey Sloan (or its predecessors)Job Title
Andrew DeLucaGiacomo Gianniotti12, 13, 1411General Surgical InternM.D.
Andrew DeLuca was an EMT before he decided to switch to being a surgical intern in Season 12. Soon after his internship begins, he starts a relationship with Maggie Pierce, but that ultimately ends when he doesn't have feelings for her anymore. In Season 14, his ex-girlfriend, Sam Bello, joins Grey Sloan, and they resume their relationship. They continue to help Amelia Shepherd together with her difficult neurosurgery endeavors.

Supporting characters[edit]

Hospital surgeons[edit]

The following listings reflect each character's status at the time of his or her first appearance on staff at Seattle Grace/Seattle Grace Mercy West/Grey Sloan Memorial.

Attending physicians[edit]

NameActor/ActressSeason(s)Episode count
Dr. Virginia DixonMary McDonnell53
An exceptional cardiothoracic surgeon who has Asperger syndrome, Dr. Dixon served as the interim Head of Cardiothoracic Surgery.

Dr. Rebecca SwenderKimberly Elise53
A surgical oncology attending assigned to oversee Izzie Stevens' cancer treatment, Dr. Swender is said to be the best surgical oncologist in the state of Washington.[2] She is a proponent for IL-2-use as treatment for cancer, citing its success when a patient, initially given only three months to live, uses the therapy and survives an additional two years. The patient, however, succumbs to complications from the inherent nature of the IL-2, which affects Swender's otherwise authoritarian and impartial persona, and casts doubt on this treatment-protocol.[3]

Dr. Margaret CampbellFaye Dunaway51
A general surgery attending, Dr. Campbell is Seattle Grace's first female surgeon. With 40 years of surgical experience, she is considered a pioneer and one of the hospital's most respected surgeons. Richard Webber may have been taught by her, which is implied when she recalls an incident involving a clamp dropped into an open body cavity. She has worked with Ellis Grey. Cristina Yang has been vocal about her objections and criticisms of Dr. Campbell's continued long-standing service. Due to a complication caused by a lacerated bowel during a routine cholecystectomy, Dr. Campbell retires after performing her last surgery to repair the "careless mistake."[4]

Dr. Robert StarkPeter MacNicol77
An incompetent pediatric surgery attending, Dr. Stark is brought in as the interim Chief of Pediatric Surgery when Arizona Robbins gives her notice to oversee a pediatric surgery program in Malawi, Africa. Under contract for a year, Dr. Stark continues to serve as the department chief when Robbins returns. Described as a lazy doctor[5] and a complacent and self-satisfied attending, he represents the antithesis of attending surgeons commonly employed at Seattle Grace/Mercy West Hospital.[6] Dr. Stark has an antagonistic disposition with most of the hospital staff, especially Alex Karev. April Kepner is the only exception to his behavior. He later attempts to date her, with little success.

Dr. Lucy FieldsRachael Taylor78
An OB/GYN attending and maternal-fetal medicine fellow at Seattle Grace Mercy West, Dr. Fields is self-proclaimed "damn good at her job." She attended Harvard Medical School and completed her OB/GYN residency at Duke University Medical Center.[7] Dr. Fields is Callie Torres' obstetrician and shows that she is equal parts tough, ironic, and empathetic, especially when dealing with Torres and her support team: Mark Sloan and Arizona Robbins. She seems to have a slight crush on Alex Karev, and they begin to form a relationship. Dr. Addison Montgomery returns and is told that she is not able to deal with traumatic pregnancy cases (such as a pregnant Callie involved in a car accident). Alex Karev breaks off his relationship with Dr. Fields in the Season 7 finale, and she goes off to treat children in Africa.[8]

Dr. Nicole HermanGeena Davis118
Nicole Herman was the Head of Fetal Surgery at Grey Sloan Memorial Hospital.Arizona worked with her as a fellow. It was revealed that she has an inoperable brain tumor and only has 6 months left. She wanted to use this period of time to teach Arizona about Fetal Surgery since it is a new field. When Amelia informed her that she believed she could remove the tumor, Herman initially rejected the idea, because she'd been given hope many times before and then had it taken away. Amelia operated and despite some complications, she successfully removed Nicole's tumor. However, she didn't wake up for several days after the surgery, leading Amelia to look for a cause. An MRI showed signs of a stroke and Amelia worried she'd never wake up. Despite this, she did eventually wake up. She was full aware of her surroundings and showed no loss of mental faculties, but she was completely blind. After being discharged from the hospital, Herman went to the Blind Institute, where she learned to live her daily life as a blind person.

Resident physicians[edit]

NameActor/ActressSeason(s)Episode count
Dr. Sydney HeronKali Rocha2, 3, 48
A fifth-year general surgery resident at Seattle Grace, Dr. Heron is known for her extremely perky personality. She initially appears as Miranda's substitute when Miranda is on maternity leave. She clashes with Cristina, who finds Sydney's positive attitude unbearable. She later serves as Izzie's peer counselor and reveals that her perky persona actually originates from a nervous breakdown she had after losing a patient of her own. Sydney is in the running to become chief resident, but loses to Callie, who is later replaced by Miranda. Sydney goes on one date with Dr. Shepherd, but dumps him when she decides he isn't ready for the kind of relationship she needs.

Dr. Reed AdamsonNora Zehetner610
Surgical resident, formerly at Mercy West Hospital, Dr. Adamson is close friends with Dr. Charles Percy and Dr. April Kepner. She seems to be attracted to Alex Karev, and has a one-night stand with Mark Sloan. She is shot in the head by Gary Clark in the Season Six finale.

Dr. Charles PercyRobert Baker6, 8, 1213
Surgical resident, formerly at Mercy West Hospital, Dr. Percy is often referred to as "the big guy." He is in love with Dr. Reed Adamson. Percy is shot by Gary Clark in the Season Six finale and, despite Miranda Bailey's efforts, he dies. He reprises his role in Season 8 in "If/Then" and later in Season 12 in "Unbreak My Heart".

Surgical interns[edit]

NameActor/ActressSeason(s)Episode count
Dr. Steve MostowMark Saul4, 5, 6, 7, 838
Dr. Mostow is a surgical intern of Dr. Cristina Yang, who calls him "2". In "There's no 'I' in Team," Dr. Yang considered "giving" him to George O'Malley when he finally passes his medical exams. Steve allows the other interns to practice an epidural anesthesia on him and introduce a catheter into his male organs. As a result, he cannot move for a while and is not present at Sadie's operation. Dr. Yang finds him immobilized and finds out about the operation, after which Steve is put on probation, along with the other interns. Steve later sleeps with fellow intern Pierce's girlfriend Megan, and she gets pregnant. Steve and Megan get married, and he is concluded to be the father. During the merger, Megan is fired, but Steve keeps his job, although Megan is later hired back by Derek Shepherd. According to his blog,[9] he has aspirations to go into neurosurgery as a specialty.

Dr. Graciela GuzmanGloria Garayua4, 5, 617
Dr. Guzman is a surgical intern of Dr. Izzie Stevens, who considers giving her to George O'Malley because she "charts like crap," but keeps her because she can put in a line. Graciela is a nervous student, who eats a lot of chocolate when she's nervous. In the episode "In The Midnight Hour," she is the only one who quits the interns' operation on Sadie because she feels it's wrong. Nevertheless, she is put on probation with the other interns.

Intern PierceJoseph Williamson4, 5, 623
Pierce is a surgical intern of Dr. Alex Karev, who considers giving him to George O'Malley just because Dr. Karev hates how his name sounds. Pierce has confronted Dr. Karev on at least one occasion, such as when he meets his punishment along with the other interns in the episode "In The Midnight Hour" and comments that Dr. Stevens killed a man and was forgiven. Dr. Karev responds by physically attacking him. Later in the season, Pierce and Steve fight over Megan, Pierce's girlfriend, who slept with Steve during a breakup. She is now pregnant without knowing who the father of her baby is.

Dr. Ryan SpaldingBrandon Scott5, 615
A surgical intern of Dr. Cristina Yang, who considers giving him to George O'Malley, Dr. Spalding first appears in the episode "Life During Wartime" and is subsequently named "4.2". In the episode "In The Midnight Hour," Ryan is one of the surgical interns operating on Dr. Sadie Harris. He is left on his own in an OR, while the others go to get help. He is put on probation with the other interns after Sadie nearly dies in the operation.

Dr. Megan MostowMolly Kidder4, 5, 625
Dr. Megan Mostow (nee Nowland) is a resident and former intern of Dr. Meredith Grey, who considers giving her to George O'Malley. She has a relationship with Intern Pierce, which ends when she has an affair with Steve that results in a pregnancy. During the hospital merger, the Chief fires her by e-mail, and she later decides to sue the hospital, believing her dismissal is related to her pregnancy. She is later rehired by Derek Shepherd, who believes she was fired unjustly and deserves a "fighting chance."

Intern LauraCandice Afia4, 5, 625
A former surgical intern under Dr. Alex Karev, Laura is rebuked by Izzie Stevens when she makes fun of a patient with a facial deformity.

Dr. Sadie HarrisMelissa George58
An intern and former best friend of Meredith, Sadie has self-harm tendencies and later quits Seattle Grace after her medical knowledge and expertise are called into question.

Dr. Norman ShalesEdward Herrmann43
An elderly surgical intern assigned to second-year Dr. Alex Karev, Dr. Shales is a former pharmacist who, because of his age, is often mistaken by patients for the senior physician. He has since transferred into psychiatry.

Dr. Heather BrooksTina Majorino9, 1022
An intern on Season 9, Dr. Brooks briefly sleeps with Dr. Alex Karev, who is having sex with intern after intern at the time. Her quick reflexes contribute to her being picked by Dr. Derek Shepherd to receive lessons in the neurosurgical field. Heather dies from complications in Season 10 premiere after being electrocuted while trying to find Dr. Richard Webber. She finds him in a pool of water and she steps onto the water before realizing that it was "live", she falls and hits her head. After she's found, Dr. Shepherd and Dr. Shane Ross operate and manage to evacuate her subdural hematoma, but her brain swells and she dies due to raised intracranial pressure.

Dr. Levi SchmittJake Borelli146
A new intern introduced in Season 14, Dr. Schmitt is widely known as the guy who's glasses fell on a patient during surgery. He has a one-night stand with Dr. Jo Wilson, but his relationship with her ends when she gets back together with Dr. Alex Karev. Dr. Schmitt begins his intern year worried about his tainted reputation, but his mentor, Dr. Meredith Grey, assures him that people don't think of him like that.

Dr. Sam BelloJeanine Mason144
A Season 14 new intern who, upon attending the new intern mixer the night before her first day, discovers that her ex-boyfriend, Dr. Andrew DeLuca, also works at Grey-Sloan Memorial. Despite their best efforts to avoid falling back into their toxic, on-again, off-again relationship, Sam and Andrew ultimately being sleeping together again.

Dr. Casey ParkerAlex Blue Davis143


Dr. Vikram RoyRushi Kota143


Dr. Taryn HelmJaicy Elliot143


Dr. Dahlia QadriSophia Taylor Ali144


Hospital Nurses[edit]

NameActor/ActressSeason(s)Episode count
Nurse Olivia HarperSarah Utterback1, 2, 3, 4, 618
A nurse at the hospital, Olivia has relationships with George and Alex. Alex gives her syphilis, which she then unknowingly gives to George after breaking up with Alex (part of a hospital-wide syphilis epidemic among the doctors and nurses). Alex begins a relationship with Izzie, who finds him cheating on her with Nurse Olivia. The female interns sometimes insultingly refer to her as "Syph Nurse." She is a member of the club "Nurses United Against Mark Sloan," which implies she has had sexual relations with him. During the merger, she is fired and Derek offers to give her a recommendation.

Nurse Tyler ChristianMoe Irvin1, 2, 3, 4, 5, 6, 7, 1026
Nurse Tyler is one of the members of the nursing staff at Seattle Grace. He attends the nurse strike in Season 2.

PatriciaRobin Pearson Rose1, 2, 3, 512
Patricia is Richard Weber's assistant/secretary and previously worked as a nurse.

Nurse RoseLauren Stamile4, 512
A nurse at the hospital, she works often with Dr. Derek Shepherd. Rose has been the attending nurse on 36 of Dr. Shepherd's surgeries (as she announced in "Forever Young," Season 4, Episode 8). Derek and Rose share a kiss and are dating, much to Meredith's distress as she tries to get over him. Despite their seemingly happy relationship, Rose is soon bothered by comments made by hospital personnel about Meredith and Derek's breakup being only temporary (which end up being true when Derek and Meredith get back together for good). Addison Montgomery sarcastically calls Rose "McRebound," unaware that Rose is in the room. Her prediction proves correct when, in the season finale "Freedom," Derek and Meredith make up and kiss. Derek abruptly leaves this kiss to break up with Rose, signaling the end of their relationship. Afterward, Rose is hostile towards Derek whenever she sees him but, when she accidentally cuts his hand during a surgery, she apologizes and transfers to peds.

Other hospital physicians[edit]

NameActor/ActressSeason(s)Episode count
Dr. Katharine WyattAmy Madigan4, 5, 618
A psychiatrist at the hospital, Katharine is Dr. Meredith Grey's and Dr. Erica Hahn's therapist. As of the episode "Sweet Surrender," Dr. Owen Hunt has begun sessions with her.

Dr. Raj SenAnjul Nigam1, 2, 47
A psychiatric resident at Seattle Grace, Dr. Sen sometimes provides consults for the surgeons.

Non-staff physicians[edit]

NameActor/ActressSeason(s)Episode count
Dr. Finn DandridgeChris O'Donnell2, 39
The former veterinarian of Meredith and Derek's dog, Doc, Finn is also the newest love interest of Meredith for some time. Meredith breaks up with him because she is still in love with Derek. Finn's wife, Liz, died in a car accident. The interns give him the nickname "McVet," along the same form as Derek Shepherd's nickname, McDreamy. He dates Meredith throughout the end of the second season, and the beginning of the third season. He competes with Derek Shepherd for Meredith's heart and ultimately loses to Derek because Meredith is still in love with Derek. Meredith realizes that he may be the "best guy," but he isn't "her guy." After she tells him this, he replies, "He'll break your heart again, Meredith, and when he does, I won't be here" and walks out for the last time.

Dr. Colin MarloweRoger Rees33
A professor at Stanford University and a brilliant cardiothoracic surgeon noted for pioneering a procedure called the Marlowe transplant, Colin Marlowe had a three-year relationship with Cristina Yang before she graduated and began her residency at Seattle Grace. He appears months later as a candidate for Chief of Surgery, and ultimately withdraws when his true purpose for joining the staff at Seattle Grace, to rekindle his relationship with Cristina, fails.

Dr. William "Will" ThorpeScott Elrod124
A surgical oncologist at Bauer Army Medical Center, William Thorpe works on Brian Carson with Dr. Meredith Grey, Dr. Callie Torres, Dr. Jackson Avery, and Dr. Jo Wilson. After the surgery is complete, Thorpe flirts with Meredith, and the two exchange numbers. Afraid to move on from Derek, Meredith dodges Thorpe's calls until he shows up to pursue her outside of Grey-Sloan Memorial. Meredith agrees to get drinks with him but freaks out again and cancels. Thorpe shows up in the lobby after Meredith's 17-hour surgery and takes her home, where they talk and eat in his car. After three dates, the two sleep together, but the next morning, Meredith feels like she cheated on Derek and kicks Thorpe out. Worried about Meredith, Thorpe visits her that night, where she admits that he is the first guy she has dated since Derek died and that she's just not ready to move on. Thorpe says he will wait for Meredith because she is worth waiting for.

Family members[edit]

Meredith Grey's family
  • Ellis Grey (Kate Burton, Sarah Paulson–1982 flashback, Sally Pressman- 1983 flashbacks): Meredith's mother and Maggie's biological mother, a highly respected surgeon who trained at Seattle Grace with Dr. Webber. During their residency, she and Webber had an affair. She left her husband Thatcher for Dr. Webber, but he could not bring himself to leave his wife. After her residency, she left Seattle to take a position at Mass General. She also worked at the Mayo Clinic. She has won the Harper Avery Award twice, and she invented the laparoscopic Grey method. She developed early-onset Alzheimer's shortly before Meredith started medical school and, at the start of the show, she has been placed in Roseridge Home for Extended Care, a nursing home. She dies of cardiac arrest in the middle of Season 3. In the episode "Drowning on Dry Land," she appears to her daughter Meredith, encouraging her to go back and live her life. She also appears in an alternate-reality episode from Season 8, called "If/then." In series 11 "She's Leaving Home", Meredith gives birth to a baby daughter, whom she names after her mother.
  • Thatcher Grey (Jeff Perry): Father of Meredith Grey and Lexie Grey. He was married to Ellis Grey, Meredith's mother, for about seven years. They divorced after she had an affair with Richard Webber. Thatcher blames Ellis somewhat for his estrangement from Meredith, saying Ellis is "cold" and won't let him get to know his daughter. After the disintegration of his first family, Thatcher remained in Seattle and married his second wife, Susan. They had two daughters, Lexie and Molly. After Meredith moves to Seattle for her residency, Susan encourages Thatcher and Meredith to develop a relationship. However, Susan's sudden death devastates Thatcher, and he blames her death on Meredith. He becomes an alcoholic, and Lexie has to give up a residency at Massachusetts General Hospital to move to Seattle to care for her father. He eventually enters rehab and apologizes to his daughters. However, his alcoholism has destroyed his liver, and Meredith has to give him a portion of hers to save his life.
  • Susan Grey (Mare Winningham) Meredith's stepmother who dies of the hiccups
  • Molly Grey-Thompson (Mandy Siegfried): Daughter of Thatcher and Susan Grey, Meredith's half-sister. She proposes to her husband, Eric, before he is shipped out by the military to be stationed in Iraq. Originally a patient at Mercy West, Molly transfers to Seattle Grace when she is 32 weeks pregnant and Addison operates to repair a congenital diaphragmatic hernia in Molly's baby. She later gives birth to a daughter, whom she names Laura.
  • Laura Thompson: Daughter of Molly Grey and Eric Thompson and Lexie's niece and Meredith's half-niece. She is born premature and kept at Seattle Grace Hospital several weeks after her birth, prompting her grandfather Thatcher Grey to hang around.
  • Margaret "Maggie" Pierce: Daughter of Ellis Grey and Richard Webber. Meredith's half-sister. Born in Boston, after Ellis and Meredith moved there, leaving Thatcher in Seattle, she was given up for adoption. She becomes a skilled heart surgeon and eventually moves to Seattle, becoming Chief of Cardio at Grey Sloan Memorial Hospital after Cristina Yang leaves.
  • Derek Shepherd (Patrick Dempsey): Meredith's husband since Season 5, legally since Season 7. Originally married to Addison Montgomery, they divorced in the third season. Derek is the father of Zola Grey Shepherd, Derek Bailey Shepherd and Ellis Shepherd. In season 11 episode 21 "How To Save A Life", he dies of a head injury after his car was T-Boned by a semi.
  • Zola Grey Shepherd: Daughter of Meredith and Derek, who is brought over with the children from Africa under the direction of Karev in Season 7. She has a spinal disease, but is treated by Derek with a shunt. They later adopt her.
  • Derek Bailey Shepherd: Son of Meredith and Derek, delivered via C-section because he is not in the correct position. While stitching Meredith up, the obstetrician who operates on Meredith is called away to another patient and an intern completes the stitching. When she begins bleeding from everywhere, Meredith diagnoses herself as in DIC. Miranda performs a spleen removal, which saves Meredith's life. Derek and Meredith name their baby after Miranda Bailey.
  • Ellis Shepherd: Second daughter of Meredith and Derek. She was born during the time jump that took place after Derek's funeral in "She's Leaving Home".

Alexandra (Lexie's) Grey's family
  • Meredith Grey (Ellen Pompeo): The daughter of Thatcher Grey and Ellis Grey. Meredith is Lexie's older half-sister whom Lexie meets at the beginning of the fourth season. Although Meredith isn't initially fond of Lexie and does not wish to know her, Meredith eventually warms up to Lexie, and the two become extremely close until Lexie's death.
  • Susan Grey (Mare Winningham): The second wife of Thatcher Grey, and mother of Lexie Grey and Molly Grey-Thompson. Susan was always aware of Thatcher's first wife and daughter, but she doesn't meet Meredith until Molly is a patient at Seattle Grace. She reaches out to Meredith and encourages her to develop a relationship with Thatcher. At first, Meredith resists Susan's attempts to mother her, but eventually comes to think of Susan as a surrogate mother. Susan dies suddenly, following a rare complication from a routine procedure to treat her acid reflux and hiccups. Thatcher is devastated by her death and became an alcoholic.
  • Thatcher Grey (Jeff Perry): Father of Meredith Grey and Lexie Grey. He was married to Ellis Grey, Meredith's mother, for about seven years. They divorced after she had an affair with Richard Webber. Thatcher blames Ellis somewhat for his estrangement from Meredith, saying Ellis is "cold" and won't let him get to know his daughter. After the disintegration of his first family, Thatcher remained in Seattle and married his second wife, Susan. They had two daughters, Lexie and Molly. After Meredith moves to Seattle for her residency, Susan encourages Thatcher and Meredith to develop a relationship. However, Susan's sudden death devastates Thatcher, and he blames her death on Meredith. He becomes an alcoholic, and Lexie has to give up a residency at Massachusetts General Hospital to move to Seattle to care for her father. He eventually enters rehab and apologizes to his daughters. However, his alcoholism has destroyed his liver, and Meredith has to give him a portion of hers to save his life.
  • Molly Grey-Thompson (Mandy Siegfried): Daughter of Thatcher and Susan Grey, Lexie's younger sister and Meredith's half-sister. She proposes to her husband, Eric, before he is shipped out by the military to be stationed in Iraq. Originally a patient at Mercy West, Molly transfers to Seattle Grace when she is 32 weeks pregnant and Addison operates to repair a congenital diaphragmatic hernia in Molly's baby. She later gives birth to a daughter, whom she names Laura.
  • Laura Thompson: Daughter of Molly Grey and Eric Thompson and Lexie's niece and Meredith's half-niece. She is born premature and kept at Seattle Grace Hospital several weeks after her birth, prompting her grandfather Thatcher Grey to hang around. Niece of Alexandra (Lexie) Grey.
  • Zola Grey Shepherd: Daughter of Meredith and Derek and half-niece's of Lexie, who is brought over with the children from Africa under the direction of Karev in Season 7. She has a spinal disease, but is treated by Derek with a shunt. They later adopt her. She is the half-niece of Alexandra (Lexie) Grey.
  • Derek Bailey Shepherd: Son of Meredith and Derek, delivered via C-section because he is not in the correct position. While stitching Meredith up, the obstetrician who operates on Meredith is called away to another patient and an intern completes the stitching. When she begins bleeding from everywhere, Meredith diagnoses herself as in DIC. Miranda performs a spleen removal, which saves Meredith's life. Derek and Meredith name their baby after Miranda Bailey. He is the half-nephew of Alexandra (Lexie) Grey, although never met by Lexie as she dies before Bailey is born.
  • Ellis Shepherd: Second daughter of Meredith and Derek and Lexie's half-niece. She was born during the time jump that took place after Derek's funeral in "She's Leaving Home". She is the half-niece of Alexandra (Lexie) Grey although Lexie never meets Ellis as she dies before the baby is born.

Derek Shepherd's family
  • Meredith Grey (Ellen Pompeo): Derek's second wife until season 11 episode 21 "How To Save A Life", when he dies of a head injury after his car is T-Boned by a semi. She is the mother of Zola, Bailey and Ellis.
  • Addison Montgomery (Kate Walsh): Derek's first wife who cheated on him with Mark. She comes to Seattle at Richard's request and the two attempt to reconcile. She ultimately moves to Los Angeles.
  • Amelia Shepherd (Caterina Scorsone): Derek's sister and the youngest Shepherd child. She and Derek witnessed their father being murdered. She became addicted to prescription medication before crashing Derek's car while under the influence. Amelia worked with Addison in Los Angeles, and is her son's godmother. She has slept with Mark (as have Nancy and Addison before her). She is currently Chief of Neuro at Grey Sloan.
  • Zola Grey Shepherd (Jela K. Moore, Heaven White): Daughter of Meredith and Derek, who is brought over with the children from Africa under the direction of Karev in Season 7. She has a spinal disease, but is treated by Derek with a shunt. They later adopt her.
  • Derek Bailey Shepherd: Son of Meredith Grey and Derek Shepherd, delivered via C-section because he is not in the correct position. While stitching Meredith up, the obstetrician who operates on Meredith is called away to another patient and an intern completes the stitching. When she begins bleeding from everywhere, Meredith diagnoses herself as in DIC. Miranda performs a spleen removal, which saves Meredith's life. Derek and Meredith name their baby after Miranda Bailey.
  • Ellis Shepherd: Second daughter of Meredith and Derek, born 9 months after Derek's death.
  • Carolyn Maloney-Shepherd (Tyne Daly): Derek's mother, who cared for Derek and his sisters after her husband was murdered.
  • Kathleen Shepherd: One of Derek's sisters; she has only been mentioned in passing and has not appeared on the show. Derek mentions she is a therapist.
  • Liz Shepherd (Neve Campbell): One of Derek's sisters. After the nerves in Derek's hand are damaged in a plane crash, she donates a nerve in her leg in order to repair his hand. Like her siblings she is a doctor though her specialty is unknown and though it is unlikely that she is a psychiatrist or a neurosurgeon.
  • Nancy Shepherd (Embeth Davidtz): One of Derek's sisters. She slept with Mark (as revealed in the episode "Let The Angels Commit"). She tells her brother, "Come on Derek. Everyone sleeps with Mark." She dislikes Meredith, and admires Addison possibly due to them both being OB/GYN doctors.
  • Alexandra "Lexie" Grey (Chyler Leigh): Becomes Derek's sister-in-law when he and Meredith Grey marry. Lexie later dies in the plane crash in the season 8 finale titled 'Flight'.
  • Margaret "Maggie" Pierce Becomes Derek's half-sister-in-law when he and Meredith Grey marry.

Cristina Yang's family
  • Helen Yang Rubenstein (Tsai Chin): Cristina's mother. Helen and Cristina's father divorced (Cristina watched her father die as they were both in a car accident), and she remarried Dr. Saul Rubenstein, an oral surgeon, when Cristina was three. She thinks Cristina should focus more on getting married and less on her career.

Izzie Stevens's family
  • Hannah Klein (Liv Hutchings): Izzie's biological daughter, born when Izzie was 16 years old. In the third season, Hannah is admitted to Seattle Grace Hospital with leukemia, and Izzie donates bone marrow to her. However, Hannah refuses to see her.
  • Robbie Stevens (Sharon Lawrence): Izzie's mother, who now works as a waitress.
  • Denny Duquette Jr. Jeffrey Dean Morgan: Izzie's fiancé for a short period of time before he died of a stroke after receiving a heart transplant. In his will he leaves Izzie $8,700,000, with which she opens the "Denny Duquette Memorial Clinic" that provides free health check ups to patients.

Richard Webber's family
  • Camille Travis (Tessa Thompson / Camille Winbush): Adele's niece, daughter of Adele's sister Arlene. She was diagnosed with ovarian cancer when she was 14, and the cancer returns when she is a senior in high school. Dr. Bailey orders the interns to plan a prom in the hospital for her.
  • Arlene Travis (Shelley Robertson): Adele's sister and Camille's mother.
  • Adele Webber (Loretta Devine): Dr. Webber's wife. Frequently frustrated by his devotion to the hospital, she eventually leaves him. She becomes pregnant with his child, but has a miscarriage. They have since reconciled. She has recently been diagnosed with Alzheimer's disease. She dies of a heart attack in the Season 9 winter premiere.
  • Catherine Avery (Debbie Allen):Richard'second wife whom he marries in season 11.
  • Margaret "Maggie" Pierce biological daughter with Ellis Grey.
George O'Malley's family
  • Harold O'Malley (George Dzundza): Father of George O'Malley, he was a truck driver with a passion for vintage cars. He was married for 40 years to his wife, Louise, and they had three sons: Jerry, Ronny, and George. He is very proud of all of his sons, but he often has trouble relating to George. He is admitted to Seattle Grace with esophageal cancer that has spread to his stomach, as well as a leaking aortic valve. He undergoes surgery to successfully replace the valve, and later has a second surgery to determine the extent of the cancer. Prior to the second surgery, he asks Dr. Webber and Dr. Bailey to remove the tumor regardless of the risk, in order to give him a chance to fight the cancer. The surgery proves too much for his body and, after several days, he goes into multi-system organ failure, which prompts the family to remove him from life support.
  • Jerry O'Malley (Greg Pitts): George's brother, who works at a dry cleaners.
  • Louise O'Malley (Debra Monk): George's mother, who works as a teacher. George seems to find her a little overbearing, and is often embarrassed by her good-natured gestures, such as setting out breakfast for the interns during rounds, and offering to iron his scrubs. She is a devout Catholic, and she is very upset when George and Callie get divorced.
  • Ronny O'Malley (Tim Griffin): George's brother, who works at the post office.
  • Callie Torres (Sara Ramirez): George's ex-wife. They get married in Las Vegas in Season 3, and later divorce in Season 4 because George is in love with Izzie.

Alex Karev's family
  • Jimmy Evans (James Remar): Alex's father, a heroin addict, who was often absent during his childhood. He used to beat Alex and Aaron, while Amber was too young during that time to recall Jimmy's behavior to her brothers. It's still unexplained how he disappeared from Alex's life, but assuming that Alex's mother died due to an illness and Alex, Aaron and Amber going through foster homes, he just left. Because of how Jimmy beat up Alex's mother, Alex became a wrestler to defend his mother. In season ten, he returns unknowingly into Alex's life, due to being brought to Grey Sloan Hospital for treatment. By then, it has been revealed that he was living as a struggling musician. After arriving in an ambulance, he asks Alex for something, which causes Alex to realize the patient might be his father. Though Alex does not want to know the result of a DNA-match suggested by Jo Wilson, she reveals the results anyway, which confirms that Jimmy is Alex's father. Alex begins secretly visiting the bar where his father starts playing after recovering and during one visit, Jimmy and Alex talk of childhood and regrets. Because Jimmy had taught Alex how to play guitar as a child, Alex assumes the discussion is about him and is goaded into playing a tune that brings memories back to Jimmy. When Alex learns that Jimmy is talking about Nicky, his son by another woman, Alex angrily beats his father up. Jimmy fails to understand Alex's anger when the latter tells Jimmy never to return to Nicky and his mother until after Alex leaves and Jimmy realizes that Alex is his son. During Jimmy's attempts to go clean, he winds up in the hospital from through withdrawal. Jo has to take care over him, which causes strain in her and Alex's relationship.
  • Aaron Karev (Jake McLaughlin): Alex's younger brother, who works as a mover. He is very nice and polite, which is why Cristina names him "Angel Spawn," while she calls Alex "Evil Spawn". He comes to Seattle Grace with a hernia, which Dr. Bailey successfully repairs. He's very chatty and tells the doctors about his and Alex's troubled childhood. He is later diagnosed with schizophrenia after he has a psychotic break and tries to kill his younger sister, Amber. As a result, he has been committed to a psychiatric ward.
  • Amber Karev: Alex's younger sister, a high school student. Aaron is trying to convince her to go to college, but she doesn't see the point.
  • Nicky Evans: Alex's younger paternal half-brother. It's assumed he still lives with his mother in South Florida.
  • Helen Karev (Lindsay Wagner): Alex's mother. Helen was diagnosed with a mental disorder but has recovered enough to resume her job at her local library. Alex and Jo visit her in Iowa in the season 14 episode 22 "Fight For Your Mind".

Miranda Bailey's family
  • Tucker Jones (Cress Williams): Miranda's ex-husband, who divorces her because she spends more time working than at home with him and Tuck. Tucker is operated on by Derek when he is involved in a car accident on his way to the hospital for their son's birth.
  • William George "Tuck" Bailey Jones: Miranda's son with her ex-husband Tucker.
  • Ben Warren (Jason George): Miranda's current husband, whom she marries in Season 9.

Mark Sloan's family
  • Grandson: Mark's grandson through Sloan, who gave him up for adoption.
  • Sloan Riley (Leven Rambin): Mark's biological daughter. As an 18-year-old, she gives birth to Mark's grandson and puts him up for adoption.
  • Sofia Robbin Sloan Torres: Mark's daughter with Callie Torres and Arizona Robbins. Conceived after Mark and Callie begin several trysts after Callie is left in the airport by Arizona Robbins, she is born prematurely on March 31, 2011, in the "Song Beneath the Song" episode.

Teddy Altman's family
  • Henry Burton (Scott Foley): Husband of Dr. Teddy Altman. She meets and marries him in Season 7 so that he can use her health insurance to cover the ongoing costs of his treatment for Von Hippel-Lindau disease. They eventually fall in love. He dies in Season 8 while undergoing surgery.

Callie Torres's family
  • Uncle Berto: Callie's uncle, whom she assumes might be gay, saying, "he hasn't been single for 60 years for no reason."
  • George O'Malley (T. R. Knight): Callie's ex-husband. They got married in Las Vegas in Season 3, and later divorced in Season 4 because George is in love with Izzie. George dies in Season 5.
  • Arizona Robbins (Jessica Capshaw): Callie's ex-wife. A pediatric surgery attending, Arizona comes from a military family.
  • Aria Torres: Callie's sister, only mentioned on the show.
  • Carlos Torres (Hector Elizondo): Father to Dr. Callie Torres. He originally is against his daughter's homosexuality and relationship with Dr. Arizona Robbins.
  • Lucia Torres (Gina Gallego): Mother to Dr. Callie Torres. She has problems with accepting her daughter's sexuality and refuses to attend her wedding to Arizona Robbins.
  • Sofia Robbin Sloan Torres: Callie's daughter, born prematurely on March 31, 2011, in the "Song Beneath the Song" episode. She is conceived after Mark and Callie begin several trysts when Callie is left in the airport by Arizona Robbins.

Arizona Robbins's family
  • Barbara Robbins (Judith Ivey): Arizona's mother.
  • Colonel Daniel Robbins, United States Marine Corps (Denis Arndt): Arizona's father.
  • Timothy Robbins: Arizona's brother, who died in the Iraq war.
  • Callie Torres (Sara Ramirez): Arizona's ex-wife and attending orthopedic surgeon at Grey Sloan Memorial Hospital.
  • Sofia Robbin Sloan Torres: Arizona's daughter, born prematurely on March 31, 2011, in the "Song Beneath the Song" episode. She is conceived after Mark and Callie begin several trysts when Callie is left in the airport by Arizona. Arizona now has sole custody of Sofia due to a family court ruling in season 12.

Jackson Avery's family
  • Dr. April Kepner: Avery's ex-wife and Trauma surgeon at Grey Sloan Memorial Hospital. April and Jackson elope, after Jackson confesses his feelings for April at the altar during her wedding to Paramedic Matthew Taylor. They have had an on and off again relationship and built in sexual tension, since Jackson took April's virginity before their Board Exam. April failed and blamed Jackson for Jesus punishing her for having sex before marriage.
  • Samuel Norbert Avery: Avery and Kepner's late son born at 24 weeks, due to type II osteogenesis imperfecta. He was baptized before dying soon after in parent's arms.
  • Harriet Kepner-Avery: Avery and Kepner's daughter. Was conceived during a moment of passion between April and Jackson in the midst of their fighting. Things aren't patched up after their one night tryst and they decided to divorce. Before signing the divorce papers, April discovered she was pregnant. Overjoyed that she could still conceive, she decided to keep the pregnancy secret out of fear that something is wrong like her last pregnancy. After a while, Arizona Robbins discovers that April is pregnant and urges her to tell Jackson and when April doesn't do it, Arizona does it herself. Jackson is at first angry but comes to understand it and they agree to raise her as co-parents. Harriet was born during a caesarean section with April under no anesthesia because April was in Meredith's kitchen and there was no way to go to the hospital. Soon Catherine comes to accept April as a mother and since Jackson and April decided to give Harriet both of their last surnames, Catherine is finally happy to see the Avery name kept alive. She was named after the famous Harriet Tubman.
  • Dr. Catherine Avery (née Fox) (Debbie Allen): Avery's mother and a brilliant urological surgeon. She appears at Seattle Grace Mercy West to perform the "first" penis transplant in the U.S. She proctors the boards in San Francisco, where she also has a one-night tryst with Dr. Webber. She and Dr. Webber eventually begin a relationship and are now married.
  • Dr. Harper Avery: Grandfather of Jackson Avery and a world-renowned surgeon.

Guest stars[edit]

Other characters[edit]

  • Joe the Bartender (Steven W. Bailey): The owner of the Emerald City Bar, located across from the hospital, where the doctors often go for a drink. Joe collapses due to an aneurysm in the episode "Raindrops Keep Falling on my Head," and Derek and Burke perform a stand-still surgery to repair it. Joe and his boyfriend Walter attend the Thanksgiving dinner Izzie hosts at Meredith's house, and they go on a camping trip with Dr. Shepherd, Preston, Richard, Alex and George. During the trip, Joe reveals during a discussion with the Chief that, although he and Walter have been "on-and-off" for about 10 years, they are now committed and considering the possibility of children. They are one of two couples being considered as adoptive parents for a young mother's twins.
  • Walter (Jack Yang): Joe's boyfriend.
  • Bonnie Crasnoff (Monica Keena): A patient admitted to Seattle Grace Hospital after being involved a train crash, she and another passenger, Tom, are connected by a large metal pole passing through their bodies. Since moving the pole would kill them, the doctors decide to move one of the patients off the pole, then operate around the pole to repair the damage in the other patient. Since her injuries are more severe, they decide to move her, and she dies almost immediately. Bonnie reappears in Season 3 as part of Meredith's dream after drowning.
  • Dennison "Denny" Duquette, Jr. (Jeffrey Dean Morgan): A patient waiting for a heart transplant, he develops a close relationship with Izzie, and eventually proposes to her. Izzie risks her career to save him by cutting his LVAD wire, ensuring that he will become so ill that he will get a new heart. He dies from a blood clot shortly after the transplant, but reappears in Season Three as part of Meredith's dream after she nearly drowns, and again in Season Five. Izzie begins to see Denny everywhere, which is eventually revealed to be a symptom of her brain tumor. He first appears in the Season Two episode "Begin the Begin," and makes his last appearance in the Season Five episode "Here's to Future Days".
  • Dylan Young (Kyle Chandler): The commanding officer of the Seattle Police Department bomb squad, he responds to the bomb scare and helps to keep Meredith calm as she holds the bomb located inside a patient's body. She removes the bomb safely from the patient, but it explodes while Dylan carries it out of the OR. He reappears in Season 3 as part of Meredith's dream after her near-drowning.
  • Amanda (Shannon Lucio): A young woman saved from being hit by a bus by George, who was himself subsequently dragged several yards by the bus and dies. Amanda is extremely concerned about him, and she stays with him in the ICU, referring to him as "her prince." She attends George's funeral and cries harder than his own mother. Amanda keeps a daily vigil outside the hospital until Izzie confronts her, pointing out that she is still alive thanks to George, and that she should honor him by living her life.
  • Rebecca Pope or "Ava" (Elizabeth Reaser): A patient with amnesia after being badly injured in the ferry crash, she is discovered by Dr. Alex Karev, and they develop a very close relationship. While at Seattle Grace, she delivers a baby girl and undergoes extensive facial reconstruction surgery, performed by Dr. Mark Sloan. She eventually regains her memory and returns home with her husband, Jeff. However, before leaving, she pleads with Alex to "give [her] a reason to stay." She returns six weeks later, claiming to be pregnant with Alex's child. Although initially upset, Alex eventually becomes excited about having a baby with her. However, she is found to have a false pregnancy. When she attempts suicide, Izzie intervenes and has her admitted to the psychiatric ward. Elizabeth Reaser was nominated for the Outstanding Guest Actress in a Drama Series at the 59th Primetime Emmy Awards, for her role on the show.
  • Gary Clark (Michael O'Neill): Husband of a patient at Seattle Grace, his wife is treated by Dr. Lexie Grey and Dr. Webber. After surgery, his wife goes into a coma and, since she has earlier signed a DNR, she is removed from life support. Clark files a lawsuit against Dr. Shepherd for wrongful death, but loses. In the Season 6 finale, he returns to the hospital intending to kill Dr. Shepherd, Dr. Lexie Grey, and Dr. Webber. He shoots several people, including Derek Shepherd, Owen Hunt, Reed Adamson, Charles Percy, and Alex Karev. After a tense standoff with Dr. Webber, he uses his last bullet to commit suicide instead of killing Dr. Webber.
  • Mary Portman (Mandy Moore): Miranda Bailey's patient during the Seattle Grace shooting, she is the wife of Bill Portman. She helps Miranda attempt to save the life of Charles Percy and, despite their efforts, he dies. She returns to the hospital six months later to have the colostomy reversal she was supposed to have had the day of the shooting. Although the surgery is successful, Mary never wakes up. She is removed from life support one month later and dies.
  • Bill Portman (Ryan Devlin): Husband of Mary Portman.

References[edit]

  1. Jump up^ "Exclusive: 'Grey's Anatomy' promotes Sarah Drew". Entertainment Weekly. Time Inc. June 9, 2010. Retrieved June 9,2010.
  2. Jump up^ "Stand By Me". Grey's Anatomy. Season 5. Episode 16. 2009-03-19. ABC.
  3. Jump up^ "Here's to the Future". Grey's Anatomy. Season 5. Episode 23. 2009-05-14. ABC.
  4. Jump up^ "An Honest Mistake". Grey's Anatomy. Season 5. Episode 16. 2009-02-19. ABC.
  5. Jump up^ Clack, Zoanne. "Grey Matter: From the Writer's of Grey's Anatomy". Archived from the original on November 22, 2010. Retrieved February 5, 2011.
  6. Jump up^ Harper, Bill. "Grey Matter: From the Writer's of Grey's Anatomy". Archived from the original on November 17, 2010. Retrieved February 5, 2011.
  7. Jump up^ Mark Wilding (writer), Kevin McKidd (director) (February 3, 2011). "Don't Deceive Me (Please Don't Go)". Grey's Anatomy. Season 7. Episode 13. ABC.
  8. Jump up^ Wilding, Bill. "Grey Matter: From the Writer's of Grey's Anatomy". Archived from the original on February 18, 2011. Retrieved February 5, 2011.
  9. Jump up^ "The Intern Formerly Known as Steve". ABC.com. 2008. Archived from the original on February 8, 2009. Retrieved April 26, 2009.

External links[edit]