September 10, 2018

Main articles: List of Grey's Anatomy cast members and List of Grey's Anatomy characters

Casting[edit]

Martin Henderson was added as a series regular for the twelfth season.
On January 23, 2014 it was reported that Ellen Pompeo and Patrick Dempsey had renewed their contracts for another two seasons, as Drs. Meredith Grey and Derek Shepherd, respectively, meaning their characters would be staying on the medical drama for seasons 11 and 12.[6] On April 24, 2015, Patrick Dempsey revealed that he would be leaving Grey's Anatomy after the eleventh season despite having a contract through another season.[7] Thus, this will be the first season in which Dr. Derek Shepherd, portrayed by Patrick Dempsey, is not included in the main cast of characters. Dempsey's character Dr. Derek Shepherd was killed off towards the end of the eleventh season in the episode "How to Save a Life", meaning he will not return for the twelfth season as previously thought. ABC put out a statement claiming Dempsey wanted to pursue other interests.[8]
On May 2, 2014, the rest of the six original cast mates, Justin Chambers, Chandra Wilson and James Pickens Jr., excluding Sandra Oh, renewed their contracts for another two seasons (11 and 12) as Drs. Alex Karev, Miranda Bailey, and Richard Webber, respectively. Sara Ramirez also renewed her contract for another two seasons as Dr. Callie Torres, which will run out after the twelfth season.[9] However, it was later announced on May 20, 2016 that Sara Ramirez, who portrayed Callie Torres for ten seasons, would leave Grey's.[10] Chambers announced on March 11, 2016, on Twitter that he will return as Dr. Alex Karev for the 13th season.[11]
On June 5, 2015, it was announced that after several seasons of being a recurring role, Jason George was upgraded to a series regular.[12] It was announced on June 15, 2015, that Martin Henderson, who played a doctor on the ShondaLand produced show Off the Map, would be added as a series regular for the twelfth season.[13] He will make his debut in the middle of the season, according to Rhimes.[14] On June 28, 2015, it was announced that Jessica Capshaw, whose contract expired after Season 11, had renewed her contract for another three seasons as Dr. Arizona Robbins. This means that her character will be staying on the show through seasons 12 as well as possible seasons 13 and 14.[15]
It was announced on September 11, 2015 that Chasing Amy actress Joey Lauren Adams would guest star as Dr. Tracy McConnell, Dr. Bailey's opponent for Chief of Surgery, and appeared in the season premiere.[16] TV veteran Bill Smitrovich was announced on November 12, 2015, to guest star as a therapist in the tenth episode of the season.[17] After appearing as Dr. Andrew DeLuca as a guest star in the first eight episodes, Giacomo Gianniotti was upgraded to a series regular on January 8, 2016.[18] It was announced on January 8, 2016 that Maya Stojan will appear in one episode as a guest star which later turned out to be Jackson's patient Tatiana whom he treated over several years.[19] On February 26, 2016, it was announced that Casey Wilson and Rita Moreno would both guest star in episode fourteen of the season.[20] Variety announced on March 8, 2016, that Wilmer Valderrama was cast as Kyle Diaz, a recurring role which he will play in a multi-episode arc.[21]

Production

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