Amelia Shepherd is the youngest sister of Derek Shepherd. She is a neurosurgeon, and was officially employed at Seaside Health and Wellness with privileges at St. Ambrose Hospital. She relocated to Seattle and took Derek's job as the Head of Neurosurgery at Grey Sloan Memorial Hospital. While in Los Angeles, she was engaged to Ryan Kerrigan until his death and later to James Peterson until she moved to Seattle. After moving to Seattle, she married Owen Hunt.